The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Jul. 18, 2017
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Igor Garkavtsev, Cambridge, MA (US);
Rakesh K. Jain, Wellesley, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 241/00 (2006.01); A61K 31/343 (2006.01); A61P 35/00 (2006.01); C07D 213/82 (2006.01); C07C 251/80 (2006.01); C07D 213/53 (2006.01);
U.S. Cl.
CPC ...
C07D 213/82 (2013.01); A61P 35/00 (2018.01); C07C 251/80 (2013.01); C07D 213/53 (2013.01);
Abstract
This invention relates to antagonists of G3BP2, G3BP1, and ZEB1. Pharmaceutical compositions comprising G3BP2 inhibitors, methods of inhibiting G3BP2, G3BP1, and ZEB1, methods of treating cancer and inflammation, and methods of identifying an inhibitor of cancer stems cells are also provided.