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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11427542 B1

PDFFull Text
Date of Patent:
Aug. 30, 2022

Filed:

Mar. 28, 2019

Compounds for treatment of cardiac arrhythmias and heart failure

Applicant:

Elex Biotech, Inc., Portland, OR (US);

Inventors:

Josephrajan Thainashmuthu, Fletcher, NC (US);

Martha Sibrian-Vazquez, Portland, OR (US);

Douglas Boatman, Petaluma, CA (US);

Assignee:

Elex Biotech, Inc., Portland, OR (US);

Attorney:

Klarquist Sparkman, LLP

Primary Examiner:

Shawquia Jackson

Int. Cl.
CPC ...
C07C 211/49 (2006.01); C07C 217/88 (2006.01); C07D 213/74 (2006.01); A61P 9/06 (2006.01); A61P 9/04 (2006.01); C07C 229/64 (2006.01); C07C 309/24 (2006.01); C07D 209/44 (2006.01); C07D 215/12 (2006.01); C07D 217/04 (2006.01); C07D 231/56 (2006.01); C07D 257/04 (2006.01); C07D 271/06 (2006.01); C07D 295/13 (2006.01);
U.S. Cl.
CPC ...
C07D 213/74 (2013.01); A61P 9/04 (2018.01); A61P 9/06 (2018.01); C07C 211/49 (2013.01); C07C 217/88 (2013.01); C07C 229/64 (2013.01); C07C 309/24 (2013.01); C07D 209/44 (2013.01); C07D 215/12 (2013.01); C07D 217/04 (2013.01); C07D 231/56 (2013.01); C07D 257/04 (2013.01); C07D 271/06 (2013.01); C07D 295/13 (2013.01);
Abstract

This disclosure concerns compounds and a method for modulating the activity of calcium ion channels, including Ca-induced (or Ca-activated) calcium release channels and conformationally coupled calcium release channels such as ryanodine receptors. Some of the compounds have a structure according to formula I, or a stereoisomer, tautomer, hydrate, solvate, prodrug, or pharmaceutically acceptable salt thereof.

Find Patent Forward Citations

Thainashmuthu, Josephrajan. (2022). Compounds for treatment of cardiac arrhythmias and heart failure (U.S. Patent No. 11427542). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11427542

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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