The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Feb. 11, 2019
Applicant:
Vistagen Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Daniel Levin, La Canada, CA;
Peter Leeming, Monrovi, CA (US);
Emerich Eisenreich, Claremont, CA (US);
Xuejun Karl Liu, Arcadia, CA (US);
Assignee:
VISTAGEN THERAPEUTICS, INC., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 227/18 (2006.01); C07C 227/16 (2006.01); C07C 227/20 (2006.01); C07C 227/32 (2006.01); C07C 227/40 (2006.01); C07C 229/36 (2006.01); C07C 229/42 (2006.01); C07C 269/06 (2006.01); C07C 271/22 (2006.01); C07C 303/28 (2006.01); C07F 3/06 (2006.01);
U.S. Cl.
CPC ...
C07C 227/18 (2013.01); C07C 227/16 (2013.01); C07C 227/20 (2013.01); C07C 227/32 (2013.01); C07C 227/40 (2013.01); C07C 229/36 (2013.01); C07C 229/42 (2013.01); C07C 269/06 (2013.01); C07C 271/22 (2013.01); C07C 303/28 (2013.01); C07F 3/06 (2013.01);
Abstract
The invention relates to an overall enantio-specific synthesis of 4-chlorokynurenine compounds, in particular L-4-chlorokynurenine, with improved yields. Large-scale syntheses are disclosed. The invention also relates to novel intermediates in the synthesis of L-4-chlorokynurenine.