The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Sep. 08, 2020
Applied Molecular Transport Inc., South San Francisco, CA (US);
Keyi Liu, Mountain View, CA (US);
Julia Dawn Mackay, Bath, GB;
Weijun Feng, Danville, CA (US);
Thomas Carl Hunter, Mountain View, CA (US);
Randall J. Mrsny, Los Altos Hills, CA (US);
Applied Molecular Transport Inc., South San Francisco, CA (US);
Abstract
The present disclosure relates to isolated non-naturally occurring delivery constructs comprising a bacterial toxin-derived delivery construct coupled to a biologically active therapeutic cargo; wherein the delivery construct is capable of delivering the biologically active cargo via transcytosis transport across an epithelial cell; and wherein the delivery construct does not comprise a bacterial toxin-derived translocation domain or a bacterial toxin-derived catalytic (cytotoxic) domain.