The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Oct. 24, 2017
Applicant:
Bethphagen Inc., Gwangju, KR;
Inventors:
Woo Jin Park, Seoul, KR;
Seung Pil Jang, Seoul, KR;
Assignee:
BethphaGen Inc., Gwangju, KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2019.01); A61P 9/12 (2006.01); A23L 33/18 (2016.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A23L 33/18 (2016.08); A61P 9/12 (2018.01); A23V 2002/00 (2013.01);
Abstract
The present invention relates to a composition comprising a protein phosphatase 1 inhibitory peptide for treating vascular diseases. The composition of the present invention inhibits protein phosphatase 1 (PP1)-mediated dephosphorylation to suppress abnormal proliferation of vascular smooth muscle cells (VSMCs), and activates eNOS of vascular endothelial cells (VECs) to induce the recovery from dysfunction, and thus can be favorably used in the treatment of vascular diseases including pulmonary hypertension.