The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2022

Filed:

Apr. 09, 2018
Applicants:

Case Western Reserve University, Cleveland, OH (US);

Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

Sanford Markowitz, Pepper Pike, OH (US);

Won Jin Ho, Cleveland, OH (US);

Yiyuan Yuan, Cleveland, OH (US);

Mukesh Jain, Solon, OH (US);

Mohamed Sabeh, Cleveland Heights, OH (US);

Joseph Ready, Carrollton, TX (US);

Noelle Williams, Dallas, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/704 (2006.01); A61P 9/00 (2006.01); A61K 31/4355 (2006.01); A61K 31/4365 (2006.01); A61K 31/437 (2006.01); A61K 31/496 (2006.01); A61K 31/519 (2006.01); A61K 31/5377 (2006.01); A61K 31/7048 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
A61K 31/704 (2013.01); A61K 31/437 (2013.01); A61K 31/4355 (2013.01); A61K 31/4365 (2013.01); A61K 31/496 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 31/7048 (2013.01); A61P 9/00 (2018.01); C07K 16/32 (2013.01);
Abstract

A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.


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