The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2022

Filed:

Mar. 06, 2018
Applicants:

Washington University, St. Louis, MO (US);

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health, Bethesda, MD (US);

Inventors:

Fumihiko Urano, St. Louis, MO (US);

Jana Mahadevan, Temecula, CA (US);

Amy Clark, St. Louis, MO (US);

Ajit Jadhav, Chantilly, VA (US);

David Maloney, Point of Rocks, MD (US);

Brandon Harvey, Parkville, MD (US);

Shyh-ming Yang, Doylestown, PA (US);

Mark Henderson, Damascus, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/554 (2006.01); A61K 9/00 (2006.01); A61K 31/155 (2006.01); A61K 31/4178 (2006.01); A61K 31/4985 (2006.01); A61K 45/06 (2006.01); C07K 14/605 (2006.01);
U.S. Cl.
CPC ...
A61K 31/554 (2013.01); A61K 9/0019 (2013.01); A61K 31/155 (2013.01); A61K 31/4178 (2013.01); A61K 31/4985 (2013.01); A61K 45/06 (2013.01); C07K 14/605 (2013.01);
Abstract

The present invention generally relates to compositions and methods for treating or preventing an endoplasmic reticulum stress disorder in subjects, including compositions and methods for treating or preventing Wolfram syndrome. The present invention also relates to methods for treating symptoms of neurodegenerative diseases.


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