The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Feb. 22, 2019
Applicant:
Case Western Reserve University, Cleveland, OH (US);
Inventor:
Jonathan S. Stamler, Shaker Heights, OH (US);
Assignee:
CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4166 (2006.01); A61P 9/00 (2006.01); A61K 31/4184 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4184 (2013.01); A61P 9/00 (2018.01); A61K 31/4166 (2013.01);
Abstract
A method of treating cardiovascular disorders and diseases in a subject in need thereof includes administering to the subject an ADH inhibitor, AKR inhibitor, and/or SNO-CoAR inhibitor at an amount(s) effective to promote S-nitrosylation of proteins in the subject, wherein the ADH inhibitor and/or SNO-CoAR inhibitor is not an ADH3 inhibitor.