The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Aug. 14, 2018
The Regents of the University of California, Oakland, CA (US);
United States As Represented BY the Department of Veterans Affairs, Washington, DC (US);
Bruce D. Hammock, Davis, CA (US);
Sung Hee Hwang, Woodland, CA (US);
Ralph W. de Vere White, Sacramento, CA (US);
Chong-xian Pan, Sacramento, CA (US);
Hongyong Zhang, Sacramento, CA (US);
Paul Henderson, Sacramento, CA (US);
Ai-Hong Ma, Sacramento, CA (US);
Maike Zimmermann, Sacramento, CA (US);
Fuli Wang, Xi'an, CN;
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);
United States as represented by the Department of Veterans Affairs, Washington, DC (US);
Abstract
Provided are methods and compositions for prolonging survival and/or reducing or inhibiting tumor growth in a cancer subject receiving a regimen of one or more chemotherapeutic agents, an inhibitor of soluble epoxide hydrolase (sEHi) and a non-steroidal anti-inflammatory drug (NSAID) that inhibits one or more enzymes selected from the group consisting of cyclo-oxygenase ('COX')-1, COX-2, and 5-lipoxygenase ('5-LOX'). The methods and compositions decrease toxicity and/or adverse side effects in subjects receiving a regimen of one or more chemotherapeutic agents.