The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2022

Filed:

Oct. 03, 2017
Applicant:

The Curators of the University of Missouri, Columbia, MO (US);

Inventors:

Kattesh Katti, Columbia, MO (US);

Cathy Cutler, Columbia, MO (US);

Menka Khoobchandani, Columbia, MO (US);

Kavita Katti, Columbia, MO (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 51/04 (2006.01); A61K 51/12 (2006.01); B22F 9/24 (2006.01); B22F 1/054 (2022.01); B22F 1/102 (2022.01); B22F 1/0545 (2022.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 9/5192 (2013.01); A61K 9/0019 (2013.01); A61K 9/5115 (2013.01); A61K 51/0491 (2013.01); A61K 51/1244 (2013.01); A61P 35/00 (2018.01); B22F 1/054 (2022.01); B22F 1/0545 (2022.01); B22F 1/102 (2022.01); B22F 9/24 (2013.01); A61K 2121/00 (2013.01); B82Y 5/00 (2013.01);
Abstract

A method for forming encapsulated gold nanoparticles mixes mangiferin into a liquid medium to form a reducing agent solution. Gold salts are mixed into the reducing agent solution. Reaction of the gold salts is permitted, in the absence of any other reducing agent, to form a nanoparticle solution of stabilized, biocompatible gold nanoparticles coated with mangiferin. The gold salts can consist of AuCl4, or can consist of radioactive gold salts. A cancer therapy method injects a solution of mangiferin encapsulated gold nanoparticles directly into a solid tumor. A solution consisting of an aqueous or alcoholic medium and mangiferin encapsulated gold nanoparticles is provided. The mangiferin encapsulated gold nanoparticles can have core sizes of ˜5-20 nm and total sizes of ˜20-120 nm.


Find Patent Forward Citations

Loading…