The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2022

Filed:

Jun. 02, 2017
Applicant:

Cedars-sinai Medical Center, Los Angeles, CA (US);

Inventors:

Maya Koronyo, Los Angeles, CA (US);

Yosef Koronyo, Los Angeles, CA (US);

Keith L. Black, Los Angeles, CA (US);

Assignee:

Cedars-Sinai Medical Center, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 15/02 (2006.01); A01K 1/03 (2006.01); A61B 3/00 (2006.01); A61B 3/02 (2006.01); A61B 3/06 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A01K 15/02 (2013.01); A01K 1/031 (2013.01); A01K 2267/0312 (2013.01); A61B 3/0091 (2013.01); A61B 3/022 (2013.01); A61B 3/06 (2013.01); A61B 5/4088 (2013.01); A61B 2503/40 (2013.01);
Abstract

Disclosed herein is a rodent and human behavioral test for evaluating visual dysfunctions associated with the retinal changes in Alzheimer disease progression. In one example, the inventors developed a maze that tests rodent's ability to identify (1) specific contrasts, (2) specific colors, (3) certain items in the visual field, and (4) other 'non-typical' peripheral and night vision functions associated with AD. For instance, the inventors developed a maze the tests the rodents ability to avoid certain colors or contrasts gradients. The maze may include certain rooms with specific visual markers (e.g., colors, contrasts, objects or other visual features) that also contain shock plates.


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