The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2022
Filed:
Jan. 28, 2021
Quantum-si Incorporated, Guilford, CT (US);
Jonathan M. Rothberg, Guilford, CT (US);
Ali Kabiri, Guilford, CT (US);
Gerard Schmid, Guilford, CT (US);
Keith G. Fife, Palo Alto, CA (US);
James Beach, Austin, TX (US);
Jason W. Sickler, Arlington, MA (US);
Lawrence C. West, San Jose, CA (US);
Paul E. Glenn, Wellesley, MA (US);
Kyle Preston, Guilford, CT (US);
Farshid Ghasemi, Guilford, CT (US);
Benjamin Cipriany, Branford, CT (US);
Jeremy Lackey, Foster City, CA (US);
Quantum-Si Incorporated, Guilford, CT (US);
Abstract
System and methods for analyzing single molecules and performing nucleic acid sequencing. An integrated device may include multiple pixels with sample wells configured to receive a sample, which when excited, emits radiation. The integrated device includes a surface having a trench region recessed from a portion of the surface and an array of sample wells, disposed in the trench region. The integrated device also includes a waveguide configured to couple excitation energy to at least one sample well in the array and positioned at a first distance from a surface of the trench region and at a second distance from the surface in a region separate from the trench region. The first distance is smaller than the second distance. The system also includes an instrument that interfaces with the integrated device. The instrument may include an excitation energy source for providing excitation energy to the integrated device by coupling to an excitation energy coupling region of the integrated device.