The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2022

Filed:

Aug. 25, 2016
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

David Feldman, Redmond, WA (US);

Daniel Sazer, Newton, MA (US);

Paul Blainey, Cambridge, MA (US);

Assignees:

THE BROAD INSTITUTE, INC., Cambridge, MA (US);

MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/686 (2018.01); B01L 3/00 (2006.01); G01N 21/25 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); B01L 3/502761 (2013.01); G01N 21/253 (2013.01); B01L 2300/0829 (2013.01); C12Q 2561/113 (2013.01); C12Q 2563/155 (2013.01); C12Q 2563/159 (2013.01); C12Q 2565/514 (2013.01); G01N 21/6452 (2013.01);
Abstract

Embodiments disclosed herein provide reagents and methods for high-throughput screening of nucleic acid sequence variations in nucleic acid containing specimens. Nucleic acid specimens to be screened are loaded into separate discrete volumes. Optically encoded particles are used to deliver primers to amplify one or more sequences comprising the nucleic acid sequence variation. The optically encoded particles may be delivered to the discrete volumes randomly resulting in a random combination of optically encoded particles in each well, or a unique combination of optically encoded particles may be specifically assigned to each discrete volume. The observable combination of optically encoded particles may then be used to identify each discrete volume.


Find Patent Forward Citations

Feldman, David. (2022). Screening of nucleic acid sequence variations via random loading of optically-encoded particles (U.S. Patent No. 11421270). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11421270

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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