The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2022
Filed:
Jul. 16, 2018
Applicant:
Conagen, Inc., Bedford, MA (US);
Inventors:
Matthew de la Pena Mattozzi, Boston, MA (US);
Daniel Kim, Carlisle, MA (US);
Sonya Clarkson, Beverley, MA (US);
Assignee:
Conagen Inc., Bedford, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/21 (2006.01); C12N 15/70 (2006.01); C12P 21/00 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/70 (2013.01); C12P 21/00 (2013.01); C12P 21/02 (2013.01); C12N 2840/002 (2013.01);
Abstract
The present invention relates to a Plasmid Addiction System for the stabilization of expression plasmids encoding proteins of interest. The invention uses a succinate cycle optimization to ensure the expression of plasmid(s) of interest. By ensuring that plasmids of interest contain genes necessary in the succinate cycle, the system ensures that the passage of the plasmid to daughters and therefore improves the efficiency of production and expression of genes and/or products of interest.