The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2022

Filed:

Oct. 24, 2019
Applicant:

The Scripps Research Institute, La Jolla, CA (US);

Inventors:

Feng Wang, Beijing, CN;

Matthew S. Tremblay, San Diego, CA (US);

Travis Young, La Jolla, CA (US);

Nicole Alvarez, San Marcos, CA (US);

Yan Liu, San Diego, CA (US);

Juanjuan Du, San Diego, CA (US);

Peter G. Schultz, La Jolla, CA (US);

Assignee:

THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/46 (2006.01); C07K 16/28 (2006.01); C07K 14/62 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2851 (2013.01); A61P 3/10 (2018.01); C07K 14/62 (2013.01); C07K 16/2854 (2013.01); C07K 2317/24 (2013.01); C07K 2319/00 (2013.01);
Abstract

Disclosed herein are immunoglobulin fusion proteins comprising an insulin therapeutic peptide and an immunoglobulin region that targets the insulin therapeutic peptide to the liver of an individual in need thereof. Further disclosed herein are compositions comprising the immunoglobulin fusion proteins and methods for using the immunoglobulin fusion proteins for the treatment or prevention of a disease or condition in a subject, for example, diabetes and diabetes related conditions.


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