The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2022

Filed:

Sep. 17, 2020
Applicant:

Abclonal Science Inc., Woburn, MA (US);

Inventors:

Yang Xiang, Winchester, MA (US);

Yan Tan, Saugus, MA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); C07K 14/165 (2006.01); C12N 5/071 (2010.01); C12N 9/22 (2006.01); C12N 15/113 (2010.01); C12N 15/85 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); C07K 14/165 (2013.01); C12N 5/0686 (2013.01); C12N 9/22 (2013.01); C12N 15/113 (2013.01); C12N 15/85 (2013.01); G01N 33/6854 (2013.01); C12N 2310/20 (2017.05); G01N 2333/165 (2013.01); G01N 2800/26 (2013.01);
Abstract

Disclosed is producing recombinant SARS-CoV-2 spike protein in a pre-fusion state, using furin knock out or knockdown mammalian cells (such as HEK293, CHO or other mammalian cells) and using them to generate antibodies and related binding agents. The antibodies/binding agents can be used in SARS-CoV-2 detection assays or in diagnosis of active or prior infection with SARS-CoV-2; in prophylaxis or as a therapeutic; or for prophylactic or therapeutic use against coronaviruses related to SARS-CoV-2.


Find Patent Forward Citations

Xiang, Yang. (2022). Binding agents to pre-fusion state sars-cov-2 spike protein (U.S. Patent No. 11421019). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11421019

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…