The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2022
Filed:
May. 04, 2020
Aclaris Therapeutics, Inc., Wayne, PA (US);
Eric Jon Jacobsen, Chesterfield, MO (US);
David Randolph Anderson, Salem, CT (US);
James Robert Blinn, O'Fallon, MO (US);
Paramita Mukherjee, Carbondale, IL (US);
Paul Changelian, Framingham, MA (US);
Canxin Xu, Ballwin, MO (US);
Other;
Abstract
The present invention relates to new pyrrolopyridine compounds having the structures of Formula (I)-(IV), wherein the R groups, A, B, C, D and n are as defined in the detailed description, and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.