The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2022

Filed:

Jun. 26, 2013
Applicants:

Samjin Pharmaceutical Co., Ltd., Seoul, KR;

Astech. Co., Ltd., Gyeonggi-do, KR;

Inventors:

Eui Hwan Cho, Seoul, KR;

Sung Ju Choi, Seoul, KR;

Sung Woo Lee, Seoul, KR;

Hee Jong Shin, Gyeonggi-do, KR;

Ho Seok Kwon, Gyeonggi-do, KR;

Jae Woong Lee, Gyeonggi-do, KR;

Jeong Ho Joo, Gyeonggi-do, KR;

Hyun Tae Kim, Gyeonggi-do, KR;

Woo Heon Song, Gyeonggi-do, KR;

Jong Bae Yoon, Gyeonggi-do, KR;

Ki Seok Park, Gyeonggi-do, KR;

Ho Joon Park, Gyeonggi-do, KR;

Ho Tae Nam, Gyeonggi-do, KR;

Assignees:

SAMJIN PHARMACEUTICAL CO., LTD., Seoul, KR;

ASTECH. CO., LTD., Gyeonggi-Do, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); C07D 215/227 (2006.01); C07D 413/12 (2006.01); A61K 31/4704 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/4704 (2013.01); C07D 215/227 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01);
Abstract

Disclosed are a novel rebamipide prodrug, a method for preparing the same, and use thereof. Also, a pharmaceutical composition comprising the novel rebamipide prodrug as an active ingredient is provided. The rebamipide prodrug is increased 25-fold in absorption rate compared to rebamipide itself, and can be applied to the prophylaxis or therapy of gastric ulcer, acute gastritis, chronic gastritis, xerophthalmia, cancer, osteoarthritis, rheumatoid arthritis, or obesity.


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