IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11420934 B1

PDFFull Text
Date of Patent:
Aug. 23, 2022

Filed:

Dec. 16, 2019

Ppar agonists

Applicants:

Salk Institute for Biological Studies, La Jolla, CA (US);

Mitobridge, Inc., Cambridge, MA (US);

Inventors:

Ronald M. Evans, La Jolla, CA (US);

Michael Downes, La Jolla, CA (US);

Thomas J. Baiga, La Jolla, CA (US);

Joseph P. Noel, La Jolla, CA (US);

Emi Kanakubo Embler, Tustin, CA (US);

Weiwei Fan, La Jolla, CA (US);

John F. W. Keana, Eugene, OR (US);

Mark G. Bock, Boston, MA (US);

Authur F. Kluge, Lincoln, MA (US);

Mike A. Patane, Andover, MA (US);

Assignees:

The Salk Institute for Biological Studies, La Jolla, CA (US);

Mitobridge, Inc., Cambridge, MA (US);

Attorney:

Klarquist Sparkman, LLP

Primary Examiner:

Samantha L Shterengarts

Int. Cl.
CPC ...
C07C 233/87 (2006.01); A61K 31/381 (2006.01); A61K 31/5377 (2006.01); A61K 31/44 (2006.01); A61K 31/4025 (2006.01); A61K 31/422 (2006.01); A61K 31/341 (2006.01); A61K 31/427 (2006.01); A61K 31/164 (2006.01); A61K 31/4178 (2006.01); C07C 255/57 (2006.01); C07C 317/44 (2006.01); C07C 233/73 (2006.01); C07C 235/42 (2006.01); C07C 235/48 (2006.01); C07C 235/84 (2006.01); C07C 237/22 (2006.01); C07C 237/32 (2006.01); C07D 309/06 (2006.01); C07D 405/04 (2006.01); C07D 405/10 (2006.01); C07D 407/12 (2006.01); C07D 413/04 (2006.01); C07D 413/10 (2006.01); C07D 413/12 (2006.01); C07D 417/04 (2006.01); C07D 417/10 (2006.01); C07D 417/12 (2006.01); C07D 207/04 (2006.01); C07D 271/12 (2006.01); C07D 209/34 (2006.01); C07D 295/13 (2006.01); C07D 305/06 (2006.01); C07D 307/83 (2006.01); C07D 231/12 (2006.01); C07D 333/24 (2006.01); C07D 405/12 (2006.01); C07D 213/56 (2006.01); C07D 307/54 (2006.01); C07C 237/48 (2006.01); C07C 259/06 (2006.01);
U.S. Cl.
CPC ...
C07C 233/87 (2013.01); A61K 31/164 (2013.01); A61K 31/341 (2013.01); A61K 31/381 (2013.01); A61K 31/4025 (2013.01); A61K 31/4178 (2013.01); A61K 31/422 (2013.01); A61K 31/427 (2013.01); A61K 31/44 (2013.01); A61K 31/5377 (2013.01); C07C 233/73 (2013.01); C07C 235/42 (2013.01); C07C 235/48 (2013.01); C07C 235/84 (2013.01); C07C 237/22 (2013.01); C07C 237/32 (2013.01); C07C 237/48 (2013.01); C07C 255/57 (2013.01); C07C 259/06 (2013.01); C07C 317/44 (2013.01); C07D 207/04 (2013.01); C07D 209/34 (2013.01); C07D 213/56 (2013.01); C07D 231/12 (2013.01); C07D 271/12 (2013.01); C07D 295/13 (2013.01); C07D 305/06 (2013.01); C07D 307/54 (2013.01); C07D 307/83 (2013.01); C07D 309/06 (2013.01); C07D 333/24 (2013.01); C07D 405/04 (2013.01); C07D 405/10 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01); C07D 413/04 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01); C07D 417/04 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07C 2601/02 (2017.05);
Abstract

Provided herein are compounds and compositions useful in increasing PPARδ activity. The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).

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