The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2022

Filed:

Jul. 02, 2020
Applicant:

Norton (Waterford) Limited, Waterford, IE;

Inventors:

Mark Milton-Edwards, Castleford, GB;

Guilherme Safioti, Helsingborg, SE;

Lena Granovsky, Petah-Tiqva, IL;

Michael Reich, Frazer, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 15/00 (2006.01); A61B 5/00 (2006.01); A61B 5/08 (2006.01); G16H 20/10 (2018.01); G16H 50/30 (2018.01); G16H 50/70 (2018.01); A61K 31/138 (2006.01); C07K 16/42 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); A61M 11/00 (2006.01);
U.S. Cl.
CPC ...
A61M 15/0001 (2014.02); A61B 5/0826 (2013.01); A61B 5/4848 (2013.01); A61B 5/7275 (2013.01); A61K 31/138 (2013.01); C07K 16/244 (2013.01); C07K 16/247 (2013.01); C07K 16/2866 (2013.01); C07K 16/4291 (2013.01); G16H 20/10 (2018.01); G16H 50/30 (2018.01); G16H 50/70 (2018.01); A61M 11/00 (2013.01); A61M 15/009 (2013.01); A61M 15/0026 (2014.02); A61M 2202/064 (2013.01); A61M 2205/3584 (2013.01); A61M 2205/502 (2013.01); A61M 2205/52 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/52 (2013.01);
Abstract

Provided is a system () for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler () for delivering a rescue medicament to the subject. The inhaler has a use-detection system (B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor () configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.


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