The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2022
Filed:
Sep. 10, 2021
Miltenyi Biotec B.v. & Co. KG, Bergisch Gladbach, DE;
Michael Lutteropp, Bergisch Gladbach, DE;
Anne Richter, Bergisch Gladbach, DE;
Andrew Kaiser, Bergisch Gladbach, DE;
Mario Assenmacher, Bergisch Gladbach, DE;
Stefan Miltenyi, Bergisch Gladbach, DE;
MILTENYI BIOTEC B.V. & CO. KG, Bergisch Gladbach, DE;
Abstract
The invention provides a system that comprises pharmaceutical agents for use in immunotherapy for reducing the side-effects of an antigen-recognizing receptor against antigen-expressing non-target cells in an individual. The system includes an antigen-recognizing receptor that specifically recognizes an antigen on target cells and at least on one hematopoietic cell type in the individual. The antigen-recognizing receptor is exemplified by chimeric antigen receptors (CAR) be expressed on the surface of an immune effector cells. The system also includes hematopoietic cells resistant to recognition of the same antigen by the antigen-recognizing receptor.