The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2022
Filed:
Oct. 25, 2018
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Richard Markham, Columbia, MD (US);
James Gordy, Baltimore, MD (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/712 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 39/385 (2006.01); C07K 14/47 (2006.01); A61P 35/00 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
A61K 39/00119 (2018.08); A61K 39/001192 (2018.08); A61K 39/385 (2013.01); A61K 39/39 (2013.01); A61K 47/6425 (2017.08); A61P 35/00 (2018.01); C07K 14/4748 (2013.01); A61K 31/712 (2013.01); A61K 2039/53 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55522 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/572 (2013.01); A61K 2039/6031 (2013.01);
Abstract
Provided herein, in some embodiments, are methods and composition for treating cancer in a subject. The methods may include administering to the subject a nucleic acid encoding MIP3α fused to a cancer antigen, administering to the subject a CpG oligodeoxynucleotide, administering to the subject interferon alpha (IFNα), and administering to the subject 5-aza-2'-deoxycytidine (Aza), in effective amounts to treat the cancer.