The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2022
Filed:
Feb. 01, 2019
Applicant:
North Carolina State University, Raleigh, NC (US);
Inventors:
Ashley Brown, Raleigh, NC (US);
Erin Sproul, Raleigh, NC (US);
Assignee:
North Carolina State University, Raleigh, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/242 (2019.01); A61K 47/58 (2017.01); A61K 47/68 (2017.01); A61K 47/69 (2017.01); A61K 33/38 (2006.01);
U.S. Cl.
CPC ...
A61K 33/242 (2019.01); A61K 33/38 (2013.01); A61K 47/58 (2017.08); A61K 47/6843 (2017.08); A61K 47/6927 (2017.08);
Abstract
Disclosed herein are platelet-like particles incorporating antimicrobial metallic nanoparticles. The platelet-like particles include an ultra-low crosslinked polymeric microgel and fibrin targeting moiety. The antimicrobial metallic nanoparticles can be covalently or noncovalently incorporated into the platelet-like particles. The particles are useful to stop bleeding and to promote wound healing while at the same time suppressing bacterial infections that can accompany tissue damage.