The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2022
Filed:
Dec. 13, 2021
Applicant:
Ammax Bio, Inc., Redwood City, CA (US);
Inventors:
Laman Alani, Menlo Park, CA (US);
Chung-Chiang Hsu, Los Altos Hills, CA (US);
Aihua Zhu, Foster City, CA (US);
Kirk William Johnson, Moraga, CA (US);
Michael Huang, Ladera Ranch, CA (US);
Assignee:
AmMax Bio, Inc., Redwood City, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 9/19 (2006.01); C07K 16/24 (2006.01); A61K 47/26 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
A61K 9/19 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01); C07K 16/243 (2013.01); C07K 16/2866 (2013.01);
Abstract
Provided are high concentration stable formulations of anti-CSF1R/CSF1 antibodies. An example formulation includes 105 to 250 mg/mL of the antibody, 100 mM to 200 mM of arginine glutamate or arginine HCl, 10 mM to 50 mM histidine, and 0.015 to 0.035 w/v % of polysorbate 80, at a pH of 5.4 to 5.6. Also provided are methods of using the formulations for treating diseases.