The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Aug. 24, 2017
Applicants:

Decipher Biosciences, Inc., San Diego, CA (US);

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Elai Davicioni, La Jolla, CA (US);

Hussam Al-Deen Ashab, Vancouver, CA;

Nicholas Erho, Vancouver, CA;

Shuang G. Zhao, Ann Arbor, MI (US);

Sei-Won Laura Chang, Ann Arbor, MI (US);

Felix Y. Feng, Hillsborough, CA (US);

Assignee:

Decipher Biosciences, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6886 (2018.01); G16B 25/10 (2019.01); G01N 33/574 (2006.01); G01N 33/48 (2006.01); G16B 20/00 (2019.01); G16H 50/30 (2018.01); G16H 50/20 (2018.01); G16B 25/20 (2019.01); G16B 40/30 (2019.01); G16B 40/20 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); G01N 33/48 (2013.01); G01N 33/574 (2013.01); G16B 20/00 (2019.02); G16B 25/10 (2019.02); G16B 25/20 (2019.02); G16H 50/20 (2018.01); G16H 50/30 (2018.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); G16B 40/20 (2019.02); G16B 40/30 (2019.02);
Abstract

Methods, compositions, and kits for identifying individuals who will be responsive to post-operative radiation therapy for treatment of prostate cancer are disclosed. In particular, the invention relates to a genomic signature based on expression levels of DNA Damage Repair genes that can be used to identify individuals likely to benefit from post-operative radiation therapy after a prostatectomy.


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