The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Apr. 13, 2018
Applicant:

Postech Academy-industry Foundation, Pohang-si, KR;

Inventors:

Won Jong Kim, Pohang-si, KR;

Ji Hyun Lee, Busan, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); A61K 31/713 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 31/713 (2013.01); C12Q 1/6886 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3519 (2013.01); C12N 2310/52 (2013.01);
Abstract

The present invention relates to a highly efficient aptamer complex comprising a branched DNA and an aptamer, and a pharmaceutical use thereof. More specifically, the aptamer complex of the present invention relates to a highly efficient aptamer complex including a Y-shaped DNA as the branched DNA and using vascular endothelial growth factor (VEGF) as a target molecule. The aptamer complex of the present invention and a pharmaceutical composition comprising the same as an active ingredient are expected to be widely used in the medical field since the binding efficiency with the target molecule is more remarkable than that of the conventional aptamer.


Find Patent Forward Citations

Loading…