The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2022
Filed:
Sep. 21, 2016
Cstone Pharmaceuticals, Grand Cayman, KY;
Cstone Pharmaceuticals (Suzhou) Co., Ltd., Suzhou, CN;
Cstone Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, CN;
Yong Zheng, Shanghai, CN;
Jing Li, Lexington, MA (US);
Gennady Gololobov, Gaithersburg, MD (US);
Xinhua Zhang, Shanghai, CN;
Baotian Yang, Shanghai, CN;
Zhewei Tang, Shanghai, CN;
Dong Li, Shanghai, CN;
Jianqing Xu, Shanghai, CN;
Zhuozhi Wang, Millbrae, CA (US);
CStone Pharmaceuticals, Grand Cayman, KY;
CStone Pharmaceuticals (Suzhou) Co., Ltd., Suzhou, CN;
CStone Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, CN;
Abstract
The present invention provides PD-1 monoclonal antibodies, particularly human monoclonal antibodies of PD-1, which specifically bind to PD-1 with high affinity and comprise a heavy chain and a light chain. The present invention further provides nucleic acid sequence encoding the antibodies of the invention, cloning or expression vectors, host cells and methods for expressing or isolating the antibodies. Immunoconjugates, therapeutic compositions comprising the antibodies of the invention are also provided. The invention also provides methods for treating various cancers with anti-PD-1 antibodies.