The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Jan. 26, 2017
Applicant:

Medimmune, Llc, Gaithersburg, MD (US);

Inventors:

Changshou Gao, Gaithersburg, MD (US);

Pamela Thompson, Gaithersburg, MD (US);

Dorin Toader, Gaithersburg, MD (US);

Nazzareno Dimasi, Gaithersburg, MD (US);

Assignee:

MedImmune, LLC, Gaithersburg, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12N 5/071 (2010.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C12N 5/0682 (2013.01); C12N 9/10 (2013.01); C07K 2317/14 (2013.01); C07K 2317/41 (2013.01); C12N 2510/02 (2013.01);
Abstract

The present disclosure relates to a process for preparing antibodies with a defined glycosylation pattern, in particular antibodies with a glycan terminating in an N-acetylglucosamine. The antibodies of the disclosure are suitable for use in a process to conjugate a payload thereto. The disclosure also extends to molecules obtained and obtainable from the process disclosed herein, novel molecules and intermediates, compositions comprising said molecules and uses of the molecules and compositions, particularly in treatment, for example in the treatment of cancer.


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