The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Aug. 24, 2018
Applicant:

Revagenix, Inc., San Mateo, CA (US);

Inventors:

Logan Andrews, San Mateo, CA (US);

Andrew Calabrese, San Mateo, CA (US);

Timothy Robert Kane, San Mateo, CA (US);

Ryan Cirz, San Mateo, CA (US);

Frederick Cohen, San Mateo, CA (US);

Michael Lopez, San Mateo, CA (US);

John Knox, San Mateo, CA (US);

Nikolai Evdokimov, San Mateo, CA (US);

Assignee:

REVAGENIX, INC., San Mateo, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/232 (2006.01); C07H 15/26 (2006.01); C07H 15/22 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
C07H 15/232 (2013.01); A61P 31/04 (2018.01); C07H 15/26 (2013.01);
Abstract

Provided herein are aminoglycoside compounds, such as compounds of formula (I), (II), (III), (IV), (IVa), (V), (VI), (VIIa), or (VIIb) or pharmaceutically acceptable salts, solvates, stereoisomers, or tautomers of any of the foregoing, useful as therapeutic or prophylactic agents. Also provided herein are methods for their preparation. The compounds may be useful in treating a bacterial infection in a subject, for example a Gram-negative bacterial infection.


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