The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Mar. 29, 2018
Applicants:

Ustav Molekularni Genetiky Av Cr, V.v.i., Prague, CZ;

Smart Brain S.r.o., Prague, CZ;

Inventors:

Michal Dvorak, Prague, CZ;

Marta Dvorakova, Prague, CZ;

Vit Karafiat, Prague, CZ;

Jan Stursa, Prague, CZ;

Lukas Werner, Velke Popovice-Brtnice, CZ;

Lucie Janeckova, Prague, CZ;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/10 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 31/704 (2006.01);
U.S. Cl.
CPC ...
C07F 9/10 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61P 35/00 (2018.01); A61K 31/704 (2013.01);
Abstract

The present invention relates to 1-acyl-lysophosphatidyl derivatives of general formula I; in which R is C4 to C30 aliphatic hydrocarbyl chain, R1 is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl, R2 is selected from H, C10 to C30 acyl or C1 to C10 alkyl, preferably C1 to C6 alkyl, and R3, when present, is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl. These derivatives are intended for the treatment of cancer, in particular melanoma, hepatocarcinoma or GIT carcinomas.


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