The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2022
Filed:
Apr. 08, 2019
Arizest (Shanghai) Pharmatech Co., Ltd., Shanghai, CN;
Jiangsu Xidi Pharmaceuticals Co., Ltd., Jiangsu, CN;
Shanghai Acebright Pharmaceuticals Group Co., Ltd., Shanghai, CN;
Deliang Niu, Shanghai, CN;
Bojun Ma, Shanghai, CN;
Zhanqun Zhu, Shanghai, CN;
Qiang Wan, Shanghai, CN;
Arizest (Shanghai) Pharmatech Co., Ltd., Shanghai, CN;
Jiangsu Xidi Pharmaceuticals Co., Ltd., Jiangsu, CN;
Shanghai Acebright Pharmaceuticals Group Co., Ltd., Shanghai, CN;
Abstract
The present invention relates to a crystal form of 3-(4-methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline monohydrochloride and the use thereof. Specifically, disclosed are a crystal form A of a monohydrochloride anhydrous substance of 3-(4-methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline monohydrochloride, a method for preparing the crystal form A and the use of the crystal form in the synthesis of nilotinib. The crystal form A of the present invention has good stability and purity, and can be directly used in the preparation and production of nilotinib. The method for preparing nilotinib in the present invention is easy to operate and has high industrial application value.