The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Dec. 20, 2016
Applicants:

The University of Chicago, Chicago, IL (US);

University of Leeds, Leeds, GB;

The J. Craig Venter Institute, Rockville, MD (US);

Institute for Systems Biology, Seattle, WA (US);

U.s. Government, As Represented BY the Secretary of the Army Medical Command (Medcom), Fort Detrick, MD (US);

The University of Strathclyde, Glasgow, GB;

Inventors:

Rima McLeod, Chicago, IL (US);

Martin McPhillie, Leeds, GB;

Colin W. G. Fishwick, Leeds, GB;

Hernan Alejandro Lorenzi, Rockville, MD (US);

Kai Wang, Seattle, WA (US);

Taek-Kyun Kim, Seattle, WA (US);

Yong Zhou, Seattle, WA (US);

Leroy E. Hood, Seattle, WA (US);

Ying Zhou, Chicago, IL (US);

Kamal El Bissati, Chicago, IL (US);

Mark Hickman, Silver Spring, MD (US);

QiGui Li, Silver Spring, MD (US);

Craig Roberts, Glasgow, GB;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/233 (2006.01); A61P 33/06 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 215/233 (2013.01); A61P 33/06 (2018.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

Disclosed herein; are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.


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