The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Jul. 09, 2018
Applicant:

Hovione Scientia Limited, Cork, IE;

Inventors:

Nuno Torres Lourenço, Lisbon, PT;

Luis Sobral, Montijo, PT;

Joana Fernandes, Lançada, PT;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 217/08 (2006.01); A61P 11/06 (2006.01); A61P 11/00 (2006.01); A61K 31/138 (2006.01); C07C 213/10 (2006.01); C07C 215/60 (2006.01);
U.S. Cl.
CPC ...
C07C 217/08 (2013.01); A61K 31/138 (2013.01); A61P 11/00 (2018.01); A61P 11/06 (2018.01); C07C 213/10 (2013.01); C07C 215/60 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to new crystalline forms of vilanterol trifenatate, processes for their preparation, and their use in a pharmaceutical composition for the treatment of respiratory diseases, particularly for the treatment of asthma and chronic obstructive pulmonary disease. In particular, the present invention relates to a crystalline form of vilanterol trifenatate characterised in that the form has an XRPD pattern as defined herein having characteristic diffraction angles (2-theta or 20 (°)) falling within or at each end of one or more of the following ranges: (a) 3 to 5°, such as 3.8 to 4.4°; and/or (b) 7 to 9.9°, such as 7 to 8.5°; and/or (c) 12 to 13.3°, such as 12 to 13.3'; and/or (d) 16.4 to 17.3°, such as 16.4 to 17.3′; and/or (e) 26.8 to 28.3°, such as 26.8 to 28.3°.


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