The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

May. 08, 2018
Applicants:

Biomagnetic Solutions Llc, State College, PA (US);

Joseph Francis Liberti, Harrison, NY (US);

Inventors:

Paul A Liberti, Naples, FL (US);

Dustin W Ritter, State College, PA (US);

Assignee:

BioMagnetic Solutions LLC, State College, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/02 (2006.01); A61M 1/36 (2006.01); A61J 1/16 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
A61M 1/0209 (2013.01); A61J 1/16 (2013.01); A61M 1/3618 (2014.02); G01N 33/585 (2013.01);
Abstract

Method consists of placing a flexible container within a rigid frame and expanding the container by pneumatic or hydraulic pressure such that the walls of the container conform to the inside walls of the rigid frame thus forming a well-defined chamber. The system has the capability of reducing the volume of the chamber by adjusting the distance between the walls of the rigid container. The methods and systems so described are applicable to closed sterile systems that employ immunomagnetic isolation or purging of components from blood products. By providing a fixed volume and at least one surface upon which targeted entities can be magnetically deposited, target cells in the case of positive isolations can be magnetically held, flushed with wash buffers over them to remove entrapped cells and finally the recovery of product of very high purifies and at high yields.


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