The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2022
Filed:
Sep. 10, 2020
Applicant:
Washington University, St. Louis, MO (US);
Inventors:
Samuel Achilefu, St. Louis, MO (US);
Kexian Liang, St. Louis, MO (US);
Rui Tang, St. Louis, MO (US);
Assignee:
WASHINGTON UNIVERSITY, St. Louis, MO (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); C07K 7/06 (2006.01); G01N 33/574 (2006.01); A61K 51/08 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0056 (2013.01); A61K 49/0032 (2013.01); A61K 49/0054 (2013.01); A61K 51/088 (2013.01); C07K 7/06 (2013.01); G01N 33/57438 (2013.01); G01N 33/57492 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention provides compounds that have motifs that target the compounds to cells that express integrins. In particular, the compounds have peptides with one or more RD motifs conjugated to an agent selected from an imaging agent and a targeting agent. The compounds may be used to detect, monitor and treat a variety of disorders mediated by integrins.