The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2022
Filed:
Apr. 14, 2017
Applicant:
University of Massachusetts, Boston, MA (US);
Inventors:
Guangping Gao, Westborough, MA (US);
Dominic Gessler, Worcester, MA (US);
Assignee:
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 38/50 (2006.01); A61K 35/761 (2015.01); A61K 35/30 (2015.01); G01N 33/574 (2006.01); C12N 9/80 (2006.01); C12N 9/10 (2006.01); A61K 38/45 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A61K 35/30 (2013.01); A61K 35/761 (2013.01); A61K 38/45 (2013.01); A61K 38/50 (2013.01); A61K 45/06 (2013.01); A61K 48/0075 (2013.01); C12N 9/1029 (2013.01); C12N 9/80 (2013.01); C12Y 203/01017 (2013.01); C12Y 305/01015 (2013.01); G01N 33/574 (2013.01); A01K 2227/105 (2013.01); A01K 2267/035 (2013.01); C12N 2750/14143 (2013.01);
Abstract
In some aspects, the disclosure relates to compositions and methods useful for the diagnosis and treatment of diseases associated with a metabolic imbalance in a subject (e.g., cancer). In some embodiments, the methods comprise administering to a subject an N-acetylaspartate (NAA)-depleting agent or an N-acetylaspartate (NAA)-increasing agent based upon the subject's metabolic profile.