The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2022
Filed:
Nov. 23, 2016
Legochem Biosciences, Inc., Daejeon, KR;
Yong Zu Kim, Daejeon, KR;
Yeong Soo Oh, Daejeon, KR;
Jeiwook Chae, Daejeon, KR;
Ho Young Song, Daejeon, KR;
Chul-Woong Chung, Daejeon, KR;
Yun Hee Park, Daejeon, KR;
Hyo Jung Choi, Daejeon, KR;
Kyung Eun Park, Daejeon, KR;
Hyoungrae Kim, Daejeon, KR;
Jinyeong Kim, Daejeon, KR;
Ji Young Min, Daejeon, KR;
Sung Min Kim, Daejeon, KR;
Byung Soo Lee, Daejeon, KR;
Dong Hyun Woo, Daejeon, KR;
Ji Eun Jung, Daejeon, KR;
Su In Lee, Daejeon, KR;
LegoChem Biosciences, Inc., Youseong-gu, KR;
Abstract
In some aspects, the invention relates to an antibody-drug conjugate, comprising an antibody; a linker; and an active agent. The antibody-drug conjugate may comprise a self-immolative group. The linker may comprise an O-substituted oxime, e.g., wherein the oxygen atom of the oxime is substituted with a group that covalently links the oxime to the active agent; and the carbon atom of the oxime is substituted with a group that covalently links the oxime to the antibody.