The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2022
Filed:
Jul. 09, 2020
Applicant:
Contrafect Corporation, Yonkers, NY (US);
Inventors:
Raymond Schuch, Mountain Lakes, NJ (US);
Simon Hoffenberg, Carmel, NY (US);
Michael Wittekind, Bainbridge Island, WA (US);
Assignee:
CONTRAFECT CORPORATION, Yonkers, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/47 (2006.01); A61K 38/12 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61K 31/7036 (2006.01); A61K 38/46 (2006.01); A61K 38/16 (2006.01); A61P 31/04 (2006.01); C12N 9/36 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); A61K 9/0019 (2013.01); A61K 9/0073 (2013.01); A61K 31/7036 (2013.01); A61K 38/12 (2013.01); A61K 38/162 (2013.01); A61K 38/46 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); C12N 9/2462 (2013.01); C12Y 302/01017 (2013.01); A61K 2121/00 (2013.01); Y02A 50/30 (2018.01);
Abstract
The present disclosure provides methods and compositions useful for the prophylactic and therapeutic amelioration and treatment of infections caused by Gram-negative bacteria, including. The disclosure further provides compositions and methods of incorporating and utilizing lysin polypeptides of the present disclosure for augmenting the efficacy of antibiotics generally suitable for the treatment of Gram-negative bacterial infection.