The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2022
Filed:
Apr. 02, 2018
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Laura Codarri Deak, Schlieren, CH;
Christian Klein, Schlieren, CH;
Laura Lauener, Schlieren, CH;
Valeria G. Nicolini, Schlieren, CH;
Stefan Seeber, Sindelsdorf, DE;
Pablo Umana, Schlieren, CH;
Inja Waldhauer, Schlieren, CH;
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Abstract
The present invention generally relates to immunoconjugates, particularly immunoconjugates comprising a mutant interleukin-2 polypeptide and an antibody that binds to PD-1. In addition, the invention relates to polynucleotide molecules encoding the immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. The invention further relates to methods for producing the mutant immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof.