The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Jun. 01, 2018
Applicant:

Juno Therapeutics, Inc., Seattle, WA (US);

Inventors:

Tina Albertson, Seattle, WA (US);

Brian Christin, Seattle, WA (US);

Jacob Randolph Garcia, Seattle, WA (US);

Christopher Glen Ramsborg, Seattle, WA (US);

Claire L. Sutherland, Seattle, WA (US);

Clinton Weber, Seattle, WA (US);

Rachel K. Yost, Seattle, WA (US);

Mark J. Gilbert, Seattle, WA (US);

He Li, Seattle, WA (US);

Assignee:

Juno Therapeutics, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61P 35/00 (2006.01); C07K 14/73 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 14/70514 (2013.01); C07K 14/70517 (2013.01);
Abstract

Provided are adoptive cell therapy methods involving the administration of doses of cells for treating disease and conditions, including certain B cell malignancies. The cells generally express recombinant receptors such as chimeric antigen receptors (CARs). In some embodiments, the methods are for treating subjects with non-Hodgkin lymphoma (NHL). In some embodiments, the methods are for treating subjects with relapsed or refractory NHL. Also provided are articles of manufacture and prophylactic treatments in connection with adoptive therapy methods.


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