The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Apr. 21, 2020
Applicants:

The Johns Hopkins University, Baltimore, MD (US);

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

David Hackam, Baltimore, MD (US);

Chhinder P. Sodhi, Columbia, MD (US);

Peter Wipf, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61K 31/7024 (2006.01); A61K 31/7028 (2006.01); A61K 31/7034 (2006.01); A61K 31/7008 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7024 (2013.01); A61K 31/7008 (2013.01); A61K 31/7028 (2013.01); A61K 31/7034 (2013.01);
Abstract

The present invention relates to methods of treating infectious, inflammatory and post-traumatic disorders by administering various compounds newly discovered to have TLR4 inhibitory activity. In addition to methods of treatment, the present invention further provides for pharmaceutical compositions comprising said compounds, together with a suitable pharmaceutical carrier.


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