The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Apr. 20, 2018
Applicant:

Hyloris Developments SA, Liège, BE;

Inventor:

Thomas Jacobsen, Liège, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/08 (2006.01); A61K 9/00 (2006.01); A61K 31/167 (2006.01); A61K 31/192 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/20 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 9/08 (2013.01); A61K 9/0019 (2013.01); A61K 31/167 (2013.01); A61K 31/192 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/20 (2013.01); A61K 47/26 (2013.01);
Abstract

The present invention provides a method for preparing an intravenously administrable aqueous composition comprising acetaminophen, and optionally one or more non-steroidal anti-inflammatory drugs (NSAIDs), whereby the dissolved oxygen of the composition in a closed container is maximally 1.0 ppm, said method comprises rinsing at least once a compounding vessel with water of a temperature of at least 80° C., thereby heating the vessel and creating an oxygen low environment in said vessel; and in said rinsed vessel dissolving acetaminophen in water for injection, said water for injection is at a temperature of at least 80° C., whereby optionally one or more NSAIDS are added prior or after dissolving of acetaminophen.


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