The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2022

Filed:

Sep. 29, 2020
Applicant:

National Institutes for Quantum Science and Technology, Chiba, JP;

Inventor:

Koichi Yamakawa, Kyoto, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/1455 (2006.01); G01N 21/55 (2014.01); A61B 5/145 (2006.01); G02F 1/35 (2006.01); G02F 1/39 (2006.01); A61B 90/30 (2016.01); A61B 90/00 (2016.01); H01S 3/16 (2006.01); H01S 3/223 (2006.01);
U.S. Cl.
CPC ...
A61B 5/1455 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); G01N 21/55 (2013.01); G02F 1/3501 (2013.01); G02F 1/39 (2013.01); A61B 2090/306 (2016.02); A61B 2090/3614 (2016.02); A61B 2562/0233 (2013.01); G02F 1/3507 (2021.01); H01S 3/1603 (2013.01); H01S 3/1643 (2013.01); H01S 3/2232 (2013.01);
Abstract

The concentration of substance in blood is measured non-invasively, with high accuracy and with simple configuration. Laser light generated by a light source is locally irradiated on the body epithelium of a subject, and the resulting diffused reflected light is detected by a light detector. The laser light has a wavelength of 9.26 μm. The laser light is generated by converting and amplifying pulsed excitation light from an excitation light source to a long wavelength. A plate-shaped window that is transparent to mid-infrared light is brought in close contact with the body epithelium. The glucose concentration in interstitial fluid can be calculated using normalized light intensity calculated from a signal ratio of signals from a monitoring light detector and the light detector.


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