The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2022
Filed:
Jun. 19, 2019
George Mason University, Fairfax, VA (US);
Mariaelena Pierobon, Fairfax, VA (US);
Emanuel Petricoin, Fairfax, VA (US);
Elisa Baldelli, Fairfax, VA (US);
George Mason University, Fairfax, VI (US);
Abstract
An embodiment relates to a method, comprising: obtaining a biological sample, performing a protein complex immunoprecipitation (Co-IP) on the sample, performing a reverse phase protein array (RPPA) on the sample after performing the protein complex immunoprecipitation, and identifying one or more protein complexes. A further embodiment relates to a method of treatment, comprising: obtaining a tissue sample from a patient, performing Co-IP then RPPA on the sample, identifying a protein complex, determining whether the protein complex comprises known protein drug targets, and treating the patient with a drug that interacts with the known protein drug targets.