The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2022
Filed:
Oct. 06, 2017
Applicant:
Oblique Therapeutics Ab, Gothenburg, SE;
Inventors:
Owe Orwar, Hovås, SE;
Carolina Trkulja, Borås, SE;
Max Davidson, Gothenburg, SE;
Jessica Hägglund, Vallentuna, SE;
Assignee:
OBLIQUE THERAPEUTICS AB, Gothenburg, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/68 (2006.01); C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
G01N 33/543 (2013.01); C12Q 1/37 (2013.01); G01N 33/6878 (2013.01); G01N 2560/00 (2013.01);
Abstract
The present invention relates to methods of identifying an epitope on a protein that can be bound by an antibody. Methods of the invention typically involve a step of limited or restricted proteolysis of a protein using a single first protease or a combination of first proteases, and a further proteolysis step using a single second protease or combination of second proteases. The invention also relates to identified epitopes and to antibodies which bind to epitopes that have been identified by methods of the invention.