The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2022

Filed:

Jun. 15, 2018
Applicant:

Koninklijke Philips N.v., Eindhoven, NL;

Inventors:

Marius Iosif Boamfa, Veldhoven, NL;

Susanne Maaike Valster, Valkenswaard, NL;

Marcus Antonius Verschuuren, Berkel-Enschot, NL;

Assignee:

KONINKLIJKE PHILIPS N.V., Eindhoven, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/27 (2006.01); G02B 21/16 (2006.01); G01N 21/64 (2006.01); G02B 21/34 (2006.01);
U.S. Cl.
CPC ...
G01N 21/278 (2013.01); G01N 21/648 (2013.01); G01N 21/6458 (2013.01); G02B 21/16 (2013.01); G02B 21/34 (2013.01); G01N 2021/6482 (2013.01);
Abstract

The present invention relates to fluorescence imaging. In order to enhance compatibility with multiple fluorescence channels for calibrating a fluorescence microscope, a calibration slide is provided that comprises a substrate and a pixel layout. The pixel layout comprises a plurality of spaced apart metal nanostructures arranged on a surface of the substrate. The metal nanostructures are arranged to produce plasmon resonances that allow absorbing light at an excitation wavelength to produce photo-luminescence and/or fluorescence light for generating a fluorescent image. The fluorescent image comprises a plurality of pixel intensity values that are provided for calibration of a fluorescence microscope.


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