The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2022

Filed:

Feb. 02, 2021
Applicant:

Wyatt Technology Corporation, Goleta, CA (US);

Inventors:

Philip J. Wyatt, Santa Barbara, CA (US);

Vincent H. Hsieh, Santa Barbara, CA (US);

Mario Yasa, Santa Barbara, CA (US);

Barbara R. Maurer, San Jose, CA (US);

David Cannell, Santa Barbara, CA (US);

Steven P. Trainoff, Santa Barbara, CA (US);

Assignee:

WYATT TECHNOLOGY CORPORATION, Goleta, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/28 (2006.01); G01N 21/05 (2006.01); G01N 30/74 (2006.01); G01N 21/51 (2006.01); B01F 25/433 (2022.01); G01N 21/47 (2006.01);
U.S. Cl.
CPC ...
G01N 1/286 (2013.01); B01F 25/4331 (2022.01); G01N 21/05 (2013.01); G01N 21/51 (2013.01); G01N 30/74 (2013.01); G01N 2001/2866 (2013.01); G01N 2021/052 (2013.01); G01N 2021/4711 (2013.01); G01N 2021/513 (2013.01);
Abstract

One or more homogenizing elements are employed in a flow through, multi-detector optical measurement system. The homogenizing elements correct for problems common to multi-detector flow-through systems such as peak tailing and non-uniform sample profile within the measurement cell. The homogenizing elements include coiled inlet tubing, a flow distributor near the inlet of the cell, and a flow distributor at the outlet of the cell. This homogenization of the sample mimics plug flow within the measurement cell and enables each detector to view the same sample composition in each individual corresponding viewed sample volume. This system is particularly beneficial when performing multiangle light scattering (MALS) measurements of narrow chromatographic peaks such as those produced by ultra-high pressure liquid chromatography (UHPLC).


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