The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2022
Filed:
Jul. 13, 2018
Fundación DE Investigación Hospital 12 DE Octubre, Madrid, ES;
Servicio Andaluz DE Salud, Seville, ES;
Conse-jo Superior DE Investigaciones Científi-cas (Csic), Seville, ES;
Luis Paz-Ares Rodríguez, Madrid, ES;
Álvaro Quintanal Villalonga, Seville, ES;
Irene Ferrer Sánchez, Madrid, ES;
Sonia Molina Pinelo, Seville, ES;
Amancio Carnero Moya, Seville, ES;
Abstract
The present invention describes a method for predicting the response of a subject suffering from lung cancer to treatment with FGFR inhibitors. The relationship between the expression of the biomarkers and the treatment response allows the subjects to be classified as responsive or unresponsive to the treatment, which facilitates the therapeutic decision-making of the attending clinician. The present invention also describes the biomarkers N-cadherin, FGFRand FGFRhow to analyse them and how to interpret the results obtained, in order to administer FGFR inhibitors only to the subjects that are responsive to the treatment, thereby optimising the same, which allows the unresponsive subjects to be treated with alternative therapies to the FGFR inhibitors.