The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2022
Filed:
Oct. 29, 2018
Applicant:
Lexent Bio, Inc., San Francisco, CA (US);
Inventors:
Samuel Levy, La Jolla, CA (US);
John C. Spinosa, La Jolla, CA (US);
Assignee:
Lexent Bio, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G16B 30/00 (2019.01); G16B 20/00 (2019.01); C12Q 1/6806 (2018.01); C12Q 1/68 (2018.01); G16B 20/20 (2019.01); G16B 30/10 (2019.01); G16B 20/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6806 (2013.01); G16B 20/00 (2019.02); G16B 20/10 (2019.02); G16B 20/20 (2019.02); G16B 30/00 (2019.02); G16B 30/10 (2019.02);
Abstract
The invention disclosed herein generally relates to methods of assessing and monitoring tumor load through analysis of tumor DNA in cancer patients. Quantitative measures derived from cell-free DNA and germline DNA are used to assess and monitor tumor load. By assessing and monitoring tumor load, cancer may be detected in a subject. The tumor load of a subject may be assessed at a number of different time points to monitor a progression, regression, or recurrence of cancer in a subject.