The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2022

Filed:

Apr. 06, 2020
Applicant:

Sutro Biopharma, Inc., South San Francisco, CA (US);

Inventors:

Martin Chandler, South San Francisco, CA (US);

Kirk Hayenga, South San Francisco, CA (US);

Henry Heinsohn, South San Francisco, CA (US);

Assignee:

Sutro Biopharma, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C12P 1/04 (2006.01); C12P 21/02 (2006.01); C07K 14/535 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); C07K 14/535 (2013.01); C07K 16/00 (2013.01); C12P 1/04 (2013.01); C12P 21/02 (2013.01);
Abstract

This invention provides for an improved method of stabilizing freeze dried bacterial extracts with a carbohydrate lyoprotectant such that the extracts can be for use in cell free protein synthesis. Also provided herein are formulations for stable, freeze dried bacterial extracts that when stored at room temperature retain at least about 70% protein synthesis activity compared to undried frozen bacterial extracts.


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